Column

Leaderboard

BronchStop recruitment by site
Rank Site Name VE Study Total
1 Leicester Royal Infirmary 106 359
2 Royal Hospital for Children, Glasgow 79 79
3 Alder Hey Children's Hospital NHS Foundation Trust 59 246
4 Addenbrooke's Hospital 57 201
5 Royal Hospital for Children & Young People, Edinburgh 53 306
6 Doncaster 43 43
7 Countess of Chester NHS Foundation Trust 41 113
8 Leighton Hospital, Mid Cheshire 29 336
9 St George's University Hospitals NHS Foundation Trust 26 90
10 Northumbria Healthcare NHS Foundation Trust 25 99

All Sites

BronchStop recruitment by site
Site Name VE Study Total
Royal Aberdeen Children's Hospital 21 87
Addenbrooke's Hospital 57 201
Alder Hey Children's Hospital NHS Foundation Trust 59 246
The Royal London 5 23
Barnet Hospital 3 143
Bristol Royal Hospital for Children 22 24
Countess of Chester NHS Foundation Trust 41 113
Colchester Hospital 21 21
Doncaster 43 43
East Cheshire NHS Trust 0 7
Royal Hospital for Children & Young People, Edinburgh 53 306
Evelina London Children's Hospital 6 133
St George's University Hospitals NHS Foundation Trust 26 90
Royal Hospital for Children, Glasgow 79 79
Ipswich Hospital 14 14
University Hospital Crosshouse 3 3
Leicester Royal Infirmary 106 359
Leighton Hospital, Mid Cheshire 29 336
Medway Hospital NHS Foundation Trust 14 14
Ninewells Hospital, Dundee 10 23
Northern Lincolnshire & Goole 12 12
Northumbria Healthcare NHS Foundation Trust 25 99
Newham Hospital 1 7
Ormskirk & District General Hospital 1 108
Poole Hospital 10 112
Royal Derby Hospital 10 52
Royal Free Hospital 14 133
Royal Preston Hospital 0 163
Rotherham NHS Foundation Trust 17 17
Salisbury NHS Foundation Trust 17 186
Sheffield Children's NHS Foundation Trust 19 141
St Helens & Knowsley NHS Trust 0 169
St Helens & Knowsley NHS Trust 0 169
South Tyneside & Sunderland NHS Foundation Trust 23 24
Watford General Hospital (West Herts NHS Trust) 2 12
Whittington Health NHS Trust 19 167
Whipps Cross 1 10

Map of Sites

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   siteID VE_study total siteName                 lat   long bstop_yn bstop_open
   <chr>     <int> <int> <chr>                  <dbl>  <dbl>    <dbl>      <dbl>
 1 LRI         106   359 Leicester Royal Infir…  52.6 -1.14         1          1
 2 GLA          79    79 Royal Hospital for Ch…  55.9 -4.34         1          1
 3 ALD          59   246 Alder Hey Children's …  53.4 -2.90         1          1
 4 ADD          57   201 Addenbrooke's Hospital  52.2  0.140        1          1
 5 EDI          53   306 Royal Hospital for Ch…  55.9 -3.14         1          1
 6 DON          43    43 Doncaster               53.5 -1.11         1         99
 7 CHS          41   113 Countess of Chester N…  53.2 -2.90         1          1
 8 MCH          29   336 Leighton Hospital, Mi…  53.1 -2.48         1          1
 9 GEO          26    90 St George's Universit…  51.4 -0.176        1          1
10 NTB          25    99 Northumbria Healthcar…  55.1 -1.58         1          0
# ℹ 27 more rows
# ℹ 1 more variable: bronchstop_complete <dbl>

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About

BronchStop is an extension of the BronchStart study which will evaluate the effectiveness of RSV vaccination in the UK.

We are recruiting children under the age of 2 years admitted with respiratory problems during the winter of 24/25 and asking which baby’s mothers were vaccinated against RSV.

Our protocol is available here.

Outputs

  1. Our early report of parent’s views on the RSV vaccine Maternal views on RSV vaccination during the first season of implementation in England and Scotland- The Lancet Infectious Diseases

  2. This is the pre print of our first in the UK assessment of the effectiveness of the vaccine against admission with RSV bronchiolitis. Bivalent prefusion F vaccination in pregnancy and respiratory syncytial virus hospitalisation in infants: results of a multi-centre, test-negative study

  3. A Radio 4 episode about the Born in Bradford cohort study. Born in Bradford - Gasping for breath

  4. One of our study team, Dr Simon Drysdale contributed to this Royal College of Paediatrics podcast discussing the maternal RSV vaccine The Paeds Round - Protecting infants with the maternal vaccine for RSV

  5. Recent World Health Organization position paper on RSV immunisation [citing the BronchStop study]. (https://www.who.int/publications/i/item/WER10022)

Column

Virus Detections

$data
# A tibble: 182 × 4
   studyWeek virus      count height
       <dbl> <chr>      <int>  <dbl>
 1         1 rsv            2     70
 2         1 adenovirus     1     20
 3         1 hMPV           0     NA
 4         1 influenza      0     50
 5         1 paraflu        0     40
 6         1 rhinovirus     1     60
 7         1 COVID19        1     30
 8         2 rsv            3     70
 9         2 adenovirus     2     20
10         2 hMPV           0     NA
# ℹ 172 more rows

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list()
attr(,"class")
[1] "element_blank" "element"      

$axis.line.x
NULL

$axis.line.x.top
NULL

$axis.line.x.bottom
NULL

$axis.line.y
NULL

$axis.line.y.left
NULL

$axis.line.y.right
NULL

$axis.line.theta
NULL

$axis.line.r
NULL

$legend.background
$fill
NULL

$colour
[1] NA

$linewidth
NULL

$linetype
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_rect" "element"     

$legend.margin
[1] 7points 7points 7points 7points

$legend.spacing
[1] 14points

$legend.spacing.x
NULL

$legend.spacing.y
NULL

$legend.key
list()
attr(,"class")
[1] "element_blank" "element"      

$legend.key.size
[1] 1lines

$legend.key.height
NULL

$legend.key.width
NULL

$legend.key.spacing
[1] 7points

$legend.key.spacing.x
NULL

$legend.key.spacing.y
NULL

$legend.frame
NULL

$legend.ticks
NULL

$legend.ticks.length
[1] 0.2 *

$legend.axis.line
NULL

$legend.text
$family
NULL

$face
NULL

$colour
NULL

$size
[1] 0.857 *

$hjust
NULL

$vjust
NULL

$angle
NULL

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$legend.text.position
NULL

$legend.title
$family
NULL

$face
NULL

$colour
NULL

$size
NULL

$hjust
[1] 0

$vjust
NULL

$angle
NULL

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$legend.title.position
NULL

$legend.position
[1] "right"

$legend.position.inside
NULL

$legend.direction
NULL

$legend.byrow
NULL

$legend.justification
[1] "left"   "center"

$legend.justification.top
NULL

$legend.justification.bottom
NULL

$legend.justification.left
NULL

$legend.justification.right
NULL

$legend.justification.inside
NULL

$legend.location
NULL

$legend.box
NULL

$legend.box.just
NULL

$legend.box.margin
[1] 0cm 0cm 0cm 0cm

$legend.box.background
list()
attr(,"class")
[1] "element_blank" "element"      

$legend.box.spacing
[1] 14points

$panel.background
list()
attr(,"class")
[1] "element_blank" "element"      

$panel.border
list()
attr(,"class")
[1] "element_blank" "element"      

$panel.spacing
[1] 7points

$panel.spacing.x
NULL

$panel.spacing.y
NULL

$panel.grid
$colour
[1] "white"

$linewidth
NULL

$linetype
NULL

$lineend
NULL

$arrow
[1] FALSE

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_line" "element"     

$panel.grid.major
$colour
[1] "grey90"

$linewidth
[1] 0.5

$linetype
NULL

$lineend
NULL

$arrow
[1] FALSE

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_line" "element"     

$panel.grid.minor
list()
attr(,"class")
[1] "element_blank" "element"      

$panel.grid.major.x
NULL

$panel.grid.major.y
NULL

$panel.grid.minor.x
NULL

$panel.grid.minor.y
NULL

$panel.ontop
[1] FALSE

$plot.background
list()
attr(,"class")
[1] "element_blank" "element"      

$plot.title
$family
NULL

$face
[1] "bold"

$colour
NULL

$size
[1] 14

$hjust
[1] 0

$vjust
NULL

$angle
NULL

$lineheight
NULL

$margin
[1] 0points 0points 7points 0points

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$plot.title.position
[1] "panel"

$plot.subtitle
$family
NULL

$face
NULL

$colour
NULL

$size
[1] 0.857 *

$hjust
[1] 0

$vjust
[1] 1

$angle
NULL

$lineheight
NULL

$margin
[1] 0points     0points     5.999points 0points    

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$plot.caption
$family
NULL

$face
NULL

$colour
NULL

$size
[1] 0.857 *

$hjust
[1] 1

$vjust
[1] 1

$angle
NULL

$lineheight
NULL

$margin
[1] 5.999points 0points     0points     0points    

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$plot.caption.position
[1] "panel"

$plot.tag
$family
NULL

$face
NULL

$colour
NULL

$size
[1] 1.2 *

$hjust
[1] 0.5

$vjust
[1] 0.5

$angle
NULL

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$plot.tag.position
[1] "topleft"

$plot.tag.location
NULL

$plot.margin
[1] 7points  14points 7points  7points 

$strip.background
$fill
[1] "grey80"

$colour
[1] "grey50"

$linewidth
[1] 0

$linetype
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_rect" "element"     

$strip.background.x
NULL

$strip.background.y
NULL

$strip.clip
[1] "inherit"

$strip.placement
[1] "inside"

$strip.text
$family
NULL

$face
NULL

$colour
NULL

$size
[1] 0.857 *

$hjust
NULL

$vjust
NULL

$angle
NULL

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$strip.text.x
NULL

$strip.text.x.bottom
NULL

$strip.text.x.top
NULL

$strip.text.y
$family
NULL

$face
NULL

$colour
NULL

$size
NULL

$hjust
NULL

$vjust
NULL

$angle
[1] -90

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$strip.text.y.left
$family
NULL

$face
NULL

$colour
NULL

$size
NULL

$hjust
NULL

$vjust
NULL

$angle
[1] 90

$lineheight
NULL

$margin
NULL

$debug
NULL

$inherit.blank
[1] TRUE

attr(,"class")
[1] "element_text" "element"     

$strip.text.y.right
NULL

$strip.switch.pad.grid
[1] 3.5points

$strip.switch.pad.wrap
[1] 3.5points

attr(,"class")
[1] "theme" "gg"   
attr(,"complete")
[1] TRUE
attr(,"validate")
[1] TRUE

$coordinates
<ggproto object: Class CoordCartesian, Coord, gg>
    aspect: function
    backtransform_range: function
    clip: on
    default: TRUE
    distance: function
    draw_panel: function
    expand: TRUE
    is_free: function
    is_linear: function
    labels: function
    limits: list
    modify_scales: function
    range: function
    render_axis_h: function
    render_axis_v: function
    render_bg: function
    render_fg: function
    reverse: none
    setup_data: function
    setup_layout: function
    setup_panel_guides: function
    setup_panel_params: function
    setup_params: function
    train_panel_guides: function
    transform: function
    super:  <ggproto object: Class CoordCartesian, Coord, gg>

$facet
<ggproto object: Class FacetNull, Facet, gg>
    attach_axes: function
    attach_strips: function
    compute_layout: function
    draw_back: function
    draw_front: function
    draw_labels: function
    draw_panel_content: function
    draw_panels: function
    finish_data: function
    format_strip_labels: function
    init_gtable: function
    init_scales: function
    map_data: function
    params: list
    set_panel_size: function
    setup_data: function
    setup_panel_params: function
    setup_params: function
    shrink: TRUE
    train_scales: function
    vars: function
    super:  <ggproto object: Class FacetNull, Facet, gg>

$plot_env
<environment: 0x55ae7fda4c00>

$layout
<ggproto object: Class Layout, gg>
    coord: NULL
    coord_params: list
    facet: NULL
    facet_params: list
    finish_data: function
    get_scales: function
    layout: NULL
    map_position: function
    panel_params: NULL
    panel_scales_x: NULL
    panel_scales_y: NULL
    render: function
    render_labels: function
    reset_scales: function
    resolve_label: function
    setup: function
    setup_panel_guides: function
    setup_panel_params: function
    train_position: function
    super:  <ggproto object: Class Layout, gg>

$labels
$labels$y
NULL

$labels$x
[1] "studyWeek"

$labels$height
[1] "count"

$labels$fill
[1] "virus"


attr(,"class")
[1] "gg"     "ggplot"

Cumulative Recruitment